Learn what Percocet is, how it works for pain relief, common side effects, and risks. Plus, treatment options if you're concerned about dependency. Percocet (oxycodone / acetaminophen) is a combination opioid medication. It's used to treat pain when non-opioid medications aren't working well enough to control pain. It's a controlled substance because it has a high risk of misuse, dependency, and addiction. Percocet is a prescription painkiller that combines two active ingredients, oxycodone and acetaminophen, to relieve moderate to severe pain. It works within 10 to 30 minutes of taking it and provides relief lasting 3 to 6 hours per dose. Percocet is a prescription painkiller combining oxycodone and acetaminophen. It's used for severe pain when other non-opioid pain treatments haven't worked or cannot be tolerated. Percocet (Oxycodone and Acetaminophen) may treat acute and moderate-to-server pain, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and drug imprint. Detailed dosage guidelines and administration information for Percocet (oxycodone hydrochloride and acetaminophen). Includes dose adjustments, warnings and precautions. Percocet® 2.5 mg/325 mg tablets (2.5 milligrams (mg) of oxycodone and 325 mg of acetaminophen): 1 or 2 tablets every 6 hours as needed. Your doctor may adjust your dose as needed. Oxycodone/paracetamol, sold under the brand name Percocet among others, [2] is a fixed-dose combination of the opioid oxycodone with paracetamol (acetaminophen), used to treat moderate to severe pain. Find patient medical information for Oxycodone/Acetaminophen (Percocet, Tylox, and others) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Percocet (oxycodone/acetaminophen) is a strong narcotic pain -reliever and cough suppressant similar to morphine, codeine, and hydrocodone. Percocet is prescribed for the relief of moderate to moderately severe pain.